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Chicken Bubble Biscuit Bake Casserole Recipe

4.7 from 107 reviews

A comforting and easy-to-make Chicken Bubble Biscuit Bake Casserole that combines tender cooked chicken, creamy vegetables, and fluffy biscuit dough baked to golden perfection, making it a perfect family-friendly meal.

Ingredients

Scale

Filling

  • 2 cups cooked chicken (shredded or diced, rotisserie works great)
  • 1 (10.5 oz) can cream of chicken soup (or cream of mushroom)
  • 1/2 cup sour cream (or plain Greek yogurt)
  • 1/2 cup milk
  • 1 cup frozen mixed vegetables (peas, carrots, corn, beans)
  • 1 tsp garlic powder
  • 1/2 tsp onion powder
  • Salt & pepper to taste

Biscuit Topping

  • 1 (16 oz) can refrigerated biscuit dough, cut into quarters
  • 1 cup shredded cheddar cheese (or mozzarella)
  • 1 tbsp melted butter (optional, for brushing)

Instructions

  1. Preheat the Oven: Preheat your oven to 350°F (175°C) and lightly grease a 9×13-inch baking dish to prevent sticking.
  2. Mix the Filling: In a large bowl, combine the cooked chicken, cream of chicken soup, sour cream, milk, frozen mixed vegetables, garlic powder, onion powder, salt, and pepper. Stir everything together until you have a smooth, well-mixed filling.
  3. Add Biscuits: Fold the quartered biscuit dough pieces gently into the chicken mixture until all biscuit pieces are coated evenly with the filling.
  4. Assemble the Casserole: Pour the entire mixture into the prepared baking dish. Evenly sprinkle the shredded cheddar cheese over the top of the casserole.
  5. Bake Covered: Cover the baking dish with foil and bake in the preheated oven for 20 minutes to allow the biscuits to start cooking and the flavors to meld.
  6. Finish Baking: Remove the foil and continue baking for another 10–15 minutes until the biscuits are puffed up, golden brown, and fully cooked through.
  7. Optional Butter Brush and Serve: If desired, brush the top of the casserole with melted butter right after baking for extra flavor and shine. Let the casserole cool slightly before serving to allow it to set.

Notes

  • You can substitute cream of mushroom soup in place of cream of chicken for a different flavor.
  • Sour cream can be replaced with plain Greek yogurt for a tangier taste and added protein.
  • Feel free to use any frozen vegetables you prefer or a mix of fresh diced vegetables.
  • Use shredded mozzarella instead of cheddar for a milder cheese option.
  • Leftover casserole reheats well in the oven or microwave.
  • For a gluten-free version, use gluten-free biscuit dough and ensure the soup is gluten-free.

Keywords: Chicken casserole, biscuit bake, comfort food, easy dinner, creamy chicken bake, cheesy chicken casserole